Cell-cell communication is vital for tissue development, and disruptions can lead to diseases.
CellPhoneDB is a bioinformatics toolkit designed to infer cell-cell communication; it's a curated repository of ligand-receptor interactions and integrations with single-cell genomics data.
CellPhoneDB v5 introduces new features, including an expanded repository with additional interactions, incorporating non-protein ligands. It offers a differentially expression-based methodology, novel computational methods for prioritizing interactions, and a visualization module called CellPhoneDBViz.